In most cases a horse fly bite can heal on. Treatment methods may include.
Biting Flies And Horses Morning Ag Clips
Culicoides are not good fliers so putting horses in a stall with a fan to produce a strong air current can be helpful.

Fly bite treatment for horses. Pyrethrin based fly sprays can also be useful to keep insects off horses. The most important aspects of fly bite treatment are stopping the horse from itching and preventing secondary infections. Treatment for fly bites is dependent upon the type or types of insects that have affected your horse.
You should cleanse the bite and apply over the counter antiseptic spray or ointment to help keep the wound clean and decrease irritation and itchiness. Topical steroids systemic steroids or a combination of both have been effective in long acting itch relief. Before this is done your horse will be bathed rinsed and dried thoroughly.
Your veterinarian may prescribe a topical medication and apply it to your horse.
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